I just got a pair of the Frogg Toggs Hellbender Guide Pants. I chose to go with the pants over chest waders since my PFD would cover the wader straps and thinking of emergency egress I opted to give the pants a try. My main objective is to keep water off of me in cooler weather and still get out and stretch my legs in shallow water.
I am 6'-0" / 170 lb / size 10 shoe. To date, I have only tried them on (dry test). They went on nicely. There seems to be ample room on legs/crotch to sit in kayak and move around as necessary, and add a base layer. The neoprene booties were neither too big nor too tight. I have not tried them with my wading boots yet. My concern, so far, is getting the booties back off my feet was tedious. I was barefoot in my trial and I normally wear graduated compression socks, which are thin and I am hoping will provide some "slippage".
Upon official un-wrapping, I will have to report back on bootie removal with socks and wet test. Hopefully it takes several in-situ tests along the coast